Toward the end of his residency in neurology at Bellevue Hospital Medical Center, Dr. Calderón understood that research was needed to determine the underpinnings of disparately poor health of communities living in poverty.
He then accepted an invitation to conduct research at the Charles R. Drew University of Medicine and Science (CDU) in Watts, South Central Los Angeles. CDU was the only historically Black and Hispanic Serving medical school west of the Mississippi River and was affiliated with Martin Luther King Jr. Hospital, where he took the position of Assistant Professor, Department of Ophthalmology; his third tour of duty.
Dr. Calderón devoted the next 25 years to academic medicine and engaged in public health related research and teaching, that addressed disparities in the health status and healthcare access affecting communities living in poverty, regardless of race, ethnicity, or national origin. While at CDU, Dr. Calderón helped to develop and went on to be Director of the Drew University Center for Cross-cultural Epidemiologic Studies (DUCES).